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1

Stereospecific cyclizations and isomerizations of cannabichromene and related cannabinoids.

B. Yagen, R. Mechoulam

Journal:

Tetrahedron Letters

Year:

1969

Language:

english

File:

PDF, 182 KB

english, 1969

2

Stereoselective cyclizations of cannabinoid 1,5 dienes.

R. Mechoulam, B. Yagen

Journal:

Tetrahedron Letters

Year:

1969

Language:

english

File:

PDF, 218 KB

english, 1969

3

The potential of sec-butylpropylacetamide (SPD) and valnoctamide and their individual stereoisomers in status epilepticus

Shekh-Ahmad, Tawfeeq, Mawasi, Hafiz, McDonough, John H., Yagen, Boris, Bialer, Meir

Journal:

Epilepsy & Behavior

Year:

2015

Language:

english

File:

PDF, 499 KB

english, 2015

4

New CNS-active drugs which are second-generation valproic acid: can they lead to the development of a magic bullet?

Isoherranen, Nina, Yagen, Boris, Bialer, Meir

Journal:

Current Opinion in Neurology

Year:

2003

Language:

english

File:

PDF, 182 KB

english, 2003

5

Reduction of the 24,25-double bond of lanosterol in vivo in the rat. Stereochemistry of the addition of the C-25 proton in the biosynthesis of cholesterol

Yagen, Boris, O'Grodnick, Joseph S., Caspi, Eliahu, Tamm, Christoph

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1974

Language:

english

File:

PDF, 856 KB

english, 1974

6

Enantioselective synthesis and teratogenicity of propylisopropyl acetamide, a CNS-active chiral amide analogue of valproic acid

Ofer Spiegelstein, Meir Bialer, Matthias Radatz, Heinz Nau, Boris Yagen

Journal:

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

7

Pharmacokinetic profile of conjugated verrucarol urinary metabolites in dogs

Shimon Barel, Boris Yagen, Meir Bialer

Journal:

Biopharmaceutics & Drug Disposition

Year:

1994

Language:

english

File:

PDF, 392 KB

english, 1994

8

Tetramethylcyclopropyl analogue of the leading antiepileptic drug, valproic acid: Evaluation of the teratogenic effects of its amide derivatives in NMRI mice

Akinobu Okada, Yuko Onishi, Boris Yagen, Jakob Avi Shimshoni, Dan Kaufmann, Meir Bialer, Michio Fujiwara

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

9

Teratology study of derivatives of tetramethylcyclopropyl amide analogues of valproic acid in mice

Akinobu Okada, Yuko Onishi, Yoshinobu Aoki, Boris Yagen, Eyal Sobol, Meir Bialer, Michio Fujiwara

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

10

Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice

Akinobu Okada, Hiroko Noyori, Boris Yagen, Jakob Avi Shimshoni, Meir Bialer, Michio Fujiwara

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2009

Language:

english

File:

PDF, 116 KB

english, 2009

11

Mutagenicity of (R) and (S) styrene 7,8-oxide and the intermediary mercapturic acid metabolites formed from styrene 7,8-oxide

Dennis A. Pagano, Boris Yagen, Oscar Hernandez, John R. Bend, Errol Zeiger

Journal:

Environmental and Molecular Mutagenesis

Year:

1982

Language:

english

File:

PDF, 521 KB

english, 1982

12

Synthesis of tritium labelled verrucarol and verrucarin a

Boris Yagen, Bruce B. Jarvis

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1989

Language:

english

File:

PDF, 332 KB

english, 1989

13

Structure–activity relationships of pyrrole amidine antiviral antibiotics III: Preparation of distamycin and congocidine derivatives based on 2,5-disubstituted pyrroles

Meir Bialer, Boris Yagen, Raphael Mechoulam, Yechiel Becker

Journal:

Journal of Pharmaceutical Sciences

Year:

1980

Language:

english

File:

PDF, 582 KB

english, 1980

14

Antiparasitic structure-activity relationships of congocidine derivatives

Meir Bialer, Joseph El-On, Boris Yagen, Raphael Mechoulam

Journal:

Journal of Pharmaceutical Sciences

Year:

1981

Language:

english

File:

PDF, 329 KB

english, 1981

15

Pharmacokinetics of the trichothecene mycotoxin verrucarol in dogs

Shimon Barel, Boris Yagen, Meir Bialer

Journal:

Journal of Pharmaceutical Sciences

Year:

1990

Language:

english

File:

PDF, 454 KB

english, 1990

16

Cucurbitacins, ‘attack’ enzymes and laccase in Botrytis cinerea

Ada Viterbo, Boris Yagen, Alfred M. Mayer

Journal:

Year:

1992

Language:

english

File:

PDF, 431 KB

english, 1992

17

Dependence of activity of cucurbitacin in repression of Botrytis laccase on its structure

Ada Viterbo, Boris Yagen, Robert Rosenthal, Alfred M. Mayer

Journal:

Year:

1993

Language:

english

File:

PDF, 313 KB

english, 1993

18

A total synthesis of distamycin a, an antiviral antibiotic

Meir Bialer, Boris Yagen, Raphael Mechoulam

Journal:

Year:

1978

Language:

english

File:

PDF, 257 KB

english, 1978

19

Synthesis and relative stereochemistry of the benzylic thioether diastereoisomers formed from glutathione and styrene oxide

Boris Yagen, Oscar Hernandez, John R. Bend, Richard H. Cox

Journal:

Bioorganic Chemistry

Year:

1981

Language:

english

File:

PDF, 764 KB

english, 1981

20

Trichothecene mycotoxins inhibit phosphoinositide hydrolysis in bovine platelets stimulated with platelet activating factor

K.M. Grandoni, P.A. Gentry, B.J. Holub, B. Yagen

Journal:

Year:

1992

Language:

english

File:

PDF, 568 KB

english, 1992

21

Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide

Eyal Sobol, Boris Yagen, John G. Lamb, H. Steve White, Bogdan J. Wlodarczyk, Richard H. Finnell, Meir Bialer

Journal:

Epilepsy Research

Year:

2007

Language:

english

File:

PDF, 283 KB

english, 2007

22

Valproic Acid: Second Generation

Meir Bialer, Boris Yagen

Journal:

Neurotherapeutics

Year:

2007

Language:

english

File:

PDF, 113 KB

english, 2007

23

Synthesis and anticonvulsant activity of aromatic tetramethylcyclopropanecarboxamide derivatives

Jakob Avi Shimshoni, Meir Bialer, Boris Yagen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 184 KB

english, 2008

24

Metabolism of a new antiepileptic drug, N-methyl-tetramethylcyclopropanecarboxamide, and anticonvulsant activity of its metabolites

Nina Isoherranen, René H Levy, Boris Yagen, José H Woodhead, H.Steve White, Meir Bialer

Journal:

Epilepsy Research

Year:

2004

Language:

english

File:

PDF, 377 KB

english, 2004

25

Stereoselective pharmacokinetic analysis of valnoctamide in healthy subjects and in patients with epilepsy*

Barel, Shimon, Yagen, Boris, Schurig, Volker, Soback, Stephan, Pisani, Francesco, Perucca, Emilio, Bialer, Meir

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 730 KB

english, 1997

26

Hydroxylation of progesterone by plant cell suspension cultures of Vinca rosea

Gilad E. Gallili, Boris Yagen, Richard I. Mateles

Journal:

Year:

1978

Language:

english

File:

PDF, 114 KB

english, 1978

27

Selective mode of action of cucurbitacin in the inhibition of laccase formation in Botrytis cinerea

Ada Viterbo, Richard C. Staples, Boris Yagen, Alfred M. Mayer

Journal:

Year:

1994

Language:

english

File:

PDF, 1.15 MB

english, 1994

28

Stereoselective oxidations of a β-methylglycal, anhydrodihydroartemisinin

Yu-Ming Pu, Boris Yagen, Herman Ziffer

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 336 KB

english, 1994

29

Novel and sensitive method for the detection of anandamide by the use of its dansyl derivative

Boris Yagen, Sumner Burstein

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 295 KB

english, 2000

30

Enantioselective analysis of levetiracetam and its enantiomer R-α-ethyl-2-oxo-pyrrolidine acetamide using gas chromatography and ion trap mass spectrometric detection

Nina Isoherranen, Michael Roeder, Stefan Soback, Boris Yagen, Volker Schurig, Meir Bialer

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 148 KB

english, 2000

31

Isolation of N,N-dialkylated derivatives of valproylglycinamide from dog plasma by active charcoal adsorption and their quantification by high-performance liquid chromatography

Ofer Spiegelstein, Meir Bialer, Boris Yagen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 336 KB

english, 1997

32

Simultaneous stereoselective high-performance liquid chromatographic determination of 10-hydroxycarbazepine and its metabolite carbamazepine-10,11-trans-dihydrodiol in human urine

Andrew Volosov, Meir Bialer, Sun Xiaodong, Emilio Perucca, Amnon Sintov, Boris Yagen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 160 KB

english, 2000

33

Valnoctamide, valpromide and valnoctic acid are much less teratogenic in mice than valproic acid

Matthias Radatz, Katharine Ehlers, Boris Yagen, Meir Bialer, Heinz Nau

Journal:

Epilepsy Research

Year:

1998

Language:

english

File:

PDF, 106 KB

english, 1998

34

Absolute configuration of the four stereoisomers of valnoctamide (2-ethyl-3-methyl valeramide), a potentially new stereospecific antiepileptic and CNS drug

Michael Roeder, Ofer Spiegelstein, Volker Schurig, Meir Bialer, Boris Yagen

Journal:

Tetrahedron: Asymmetry

Year:

1999

Language:

english

File:

PDF, 290 KB

english, 1999

35

Gas chromatographic determination of novel valproyl taurinamide derivatives in mouse and dog plasma

Nina Isoherranen, Boris Yagen, Ofer Spiegelstein, Amir Steinman, Richard H Finnell, Meir Bialer

Journal:

Journal of Chromatography B

Year:

2003

Language:

english

File:

PDF, 647 KB

english, 2003

36

Pharmacokinetics of Levetiracetam and Its Enantiomer (R)-α-ethyl-2-oxo-pyrrolidine acetamide in Dogs

Nina Isoherranen, Boris Yagen, Stefan Soback, Michael Roeder, Volker Schurig, Meir Bialer

Journal:

Year:

2001

Language:

english

File:

PDF, 337 KB

english, 2001

37

Anticonvulsant Profile and Teratogenicity of N-methyl-tetramethylcyclopropyl Carboxamide: A New Antiepileptic Drug

Nina Isoherranen, H. Steve White, Richard H. Finnell, Boris Yagen, José H. Woodhead, Gregory D. Bennett, Karen S. Wilcox, Matthew E. Barton, Meir Bialer

Journal:

Year:

2002

Language:

english

File:

PDF, 257 KB

english, 2002

38

Developmental Outcome of Levetiracetam, Its Major Metabolite in Humans, 2-Pyrrolidinone N-Butyric Acid, and Its Enantiomer (R)-α-ethyl-oxo-pyrrolidine Acetamide in a Mouse Model of Teratogenicity

Nina Isoherranen, Ofer Spiegelstein, Meir Bialer, Jing Zhang, Michelle Merriweather, Boris Yagen, Michael Roeder, Aleata A. Triplett, Volker Schurig, Richard H. Finnell

Journal:

Year:

2003

Language:

english

File:

PDF, 210 KB

english, 2003

39

The cytotoxicity of T-2 toxin and related 12,13-epoxytrichothecenes to Adriamycin-sensitive and-resistant P388 leukemia cells

Avner Ramu, Boris Yagen, Nili Ramu

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1989

Language:

english

File:

PDF, 384 KB

english, 1989

40

Toxic and lethal effects of T-2 toxin upon intracerebral administration to rats

Felix Bergmann, Boris Yagen, Dov Soffer

Journal:

Archives of Toxicology

Year:

1985

Language:

english

File:

PDF, 1.46 MB

english, 1985

41

Structure-activity relationships for the direct toxic action of trichothecenes on rat brain

Felix Bergmann, Boris Yagen

Journal:

Archives of Toxicology

Year:

1989

Language:

english

File:

PDF, 194 KB

english, 1989

42

Comparative study of the yield of T-2 toxic produced by Fusarium poae, F. sporotrichioides and F. sporotrichioides var. tricinctum strains from different sources

A. Z. Joffe, B. Yagen

Journal:

Year:

1977

Language:

english

File:

PDF, 903 KB

english, 1977

43

T-2 toxin effect on isolated perfused rat hearts

R. Yarom, R. More, S. Raz, Y. Shimoni, O. Sarel, B. Yagen

Journal:

Basic Research in Cardiology

Year:

1983

Language:

english

File:

PDF, 1.08 MB

english, 1983

44

Protective effect of vitamins against trichothecene toxicity towardsSaccharomyces cerevisiae

B. Yagen, S. Halevy

Journal:

Cellular and Molecular Life Sciences

Year:

1987

Language:

english

File:

PDF, 397 KB

english, 1987

45

New, sensitive thin-layer chromatographic-high-performance liquid chromatographic method for detection of trichothecene mycotoxins

Boris Yagen, Amnon Sintov, Meir Bialer

Journal:

Journal of Chromatography A

Year:

1986

Language:

english

File:

PDF, 680 KB

english, 1986

46

Induction of laccase formation in Botrytis and its inhibition by cucurbitacin: Is gallic acid the true inducer?

Ada Viterbo, Boris Yagen, Alfred M. Mayer

Journal:

Year:

1993

Language:

english

File:

PDF, 354 KB

english, 1993

47

CD additivity in trichothecene benzoates: application as a microanalytical method for trichothecene characterization

Eugene M. Oltz, Koji Nakanishi, Boris Yagen, David G. Corley, George E. Rottinghaus, Michael S. Tempesta

Journal:

Year:

1986

Language:

english

File:

PDF, 583 KB

english, 1986

48

Gas chromatographic assay with pharmacokinetic applications for monitoring T-2 and HT-2 toxins in plasma

Boris Yagen, Meir Bialer, Amnon Sintov

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1985

Language:

english

File:

PDF, 526 KB

english, 1985

49

The Activity of Antiepileptic Drugs as Histone Deacetylase Inhibitors

Sara Eyal, Boris Yagen, Eyal Sobol, Yoram Altschuler, Miriam Shmuel, Meir Bialer

Journal:

Year:

2004

Language:

english

File:

PDF, 157 KB

english, 2004

50

Structure-Pharmacokinetic-Pharmacodynamic Relationships of yV-Alkyl Derivatives of the New Antiepileptic Drug Valproyl Glycinamide

Ofer Spiegelstein, Boris Yagen, Meir Bialer

Journal:

Year:

1999

Language:

english

File:

PDF, 734 KB

english, 1999

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